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In contrast, high dietary zinc/zinc overload generally led to either unchanged or decreased α-diversity, decreased short-chain fatty acids, and an increase in bacterial gene expression for proteins involved in metal and antibiotic resistance [144].” 5.2Metabolic endotoxemia Metabolic endotoxemia is defined as a diet-induced 2- to 3-fold increase in plasma LPS associated with low-grade inflammation, ultimately leading to the development of cardiometabolic diseases [145,146]
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